Heat-shock protein 60 kDa and atherogenic dyslipidemia in patients with untreated mild periodontitis: a pilot study
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منابع مشابه
The 60-kDa heat shock protein modulates allograft rejection.
Allograft rejection is a process of immune reactivity triggered by foreign transplantation antigens. We now demonstrate that the 60-kDa heat shock protein (hsp60), a molecule that is identical in the donor and the recipient, can regulate allograft immunity. In wild-type mice, hsp60 expression was greatly enhanced in allografts being rejected. By using MHC class II (Ealpha) promoter hsp60 transg...
متن کاملHuman 60-kDa heat-shock protein: a danger signal to the innate immune system.
Mammalian 60-kDa heat-shock protein (hsp60) is a key target of T cell and Ab responses in chronic inflammation or atherosclerosis. We show in this study that human hsp60 is also an Ag recognized by cells of the innate immune system, such as macrophages. Both mouse and human macrophages respond to contact with exogenous human hsp60 with rapid release of TNF-alpha; mouse macrophages in addition p...
متن کاملThe production of molecular clones of Toxoplasma gondii-derived heat shock protein 70 kDa
Toxoplasmosis is a common and widespread infection in humans and many other species of warm–blooded animals. Toxoplasma gondii-derived heat shock protein 70 (Hsp70) may play an important role in the virulence of Toxoplasma gondii (T. gondii). In the present study, T. gondii Hsp70 was amplified by polymerase chain reaction (PCR) from the DNA of the T. gondiitachyzoite RH strain through the use o...
متن کاملExpression of Heat Shock Protein 60 kDa Is Upregulated in Cervical Cancer
PURPOSE Cervical cancer caused by the human papilloma virus (HPV) continues to be the cause of yearly death among women. However, it is a curable disease when diagnosed at an early stage. Recently, several researches have reported that heat shock protein (HSP) 60, a chaperone protein of molecular weight of 60 kDa, is involved in carcinogenesis and apoptosis. In order to evaluate the prognostic ...
متن کاملRelationship of anti-60 kDa heat shock protein and anti-cholesterol antibodies to cardiovascular events.
BACKGROUND Several recent studies have indicated an association between key inflammatory mediators and atherosclerotic diseases. We evaluated whether high levels of antibodies against heat shock proteins and cholesterol (ACHA) predicted cardiovascular (CV) events. METHODS AND RESULTS We used blood samples from the Heart Outcomes Prevention Evaluation (HOPE) study to conduct a nested case-cont...
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ژورنال
عنوان ژورنال: Cell Stress and Chaperones
سال: 2012
ISSN: 1355-8145,1466-1268
DOI: 10.1007/s12192-011-0315-1